Basolateral potassium channel in turtle colon. Evidence for single-file ion flow.
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چکیده
منابع مشابه
Basolateral potassium channel in turtle colon. Evidence for single-file ion flow
Treatment of the apical surface of the isolated, ouabain-inhibited turtle colon with the polyene antibiotic amphotericin B permitted the properties of a barium-sensitive potassium conductance in the basolateral membrane to be discerned from the measurements of transepithelial fluxes and electrical currents. Simultaneous measurements of potassium currents and 42K fluxes showed that the movement ...
متن کاملAn evidence for a potassium channel in endoplasmic reticulum based on single channel recording in bilayer lipid membrane
Introduction Numerous studies have demonstrated the presence of potassium selective channels in membranes internal organelles. These channels are essential to a large variety of cellular processes including intracellular 2+ a signaling, protein recycling, charge neutralization and cell protection. In contrast to the sarcoplasmic reticulum + here potassium channels have been clearly ...
متن کاملCation Activation of the Basolateral Sodium-Potassium Pump in Turtle Colon
The current generated by electrogenic sodium-potassium exchange at the basolateral membrane of the turtle colon can be measured directly in tissues that have been treated with serosal barium (to block the basolateral potassium conductance) and mucosal amphotericin B (to reduce the cation selectivity of the apical membrane). We studied the activation of this pump current by mucosal sodium and se...
متن کاملResting and osmotically induced basolateral K conductances in turtle colon
Two types of K conductance can be distinguished in the basolateral membranes of polyene-treated colonic epithelial cells (see Germann, W. J., M. E. Lowy, S. A. Ernst, and D. C. Dawson, 1986, Journal of General Physiology, 88:237-251). The significance of these two types of K conductance was investigated by measuring the properties of the basolateral membrane under conditions that we presumed wo...
متن کاملan evidence for a potassium channel in endoplasmic reticulum based on single channel recording in bilayer lipid membrane
introduction numerous studies have demonstrated the presence of potassium selective channels in membranes internal organelles. these channels are essential to a large variety of cellular processes including intracellular 2+ a signaling, protein recycling, charge neutralization and cell protection. in contrast to the sarcoplasmic reticulum + here potassium channels have been clearly identified, ...
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ژورنال
عنوان ژورنال: Journal of General Physiology
سال: 1983
ISSN: 0022-1295,1540-7748
DOI: 10.1085/jgp.82.3.297